appearance of acute myelogenous leukemia (aml) in a patient with breast cancer after adjuvant chemotherapy: case report and review of the literature

Authors

mehrdad payandeh dept. of hematology, oncology, kermanshah university of medical sciences, kermanshah, iran

reza khodarahmi medical biology research center, kermanshah university of medical sciences, kermanshah, iran

masoud sadeghi students research committee, kermanshah university of medical sciences, kermanshah, iran

edris sadeghi students research committee, kermanshah university of medical sciences, kermanshah, iran

abstract

1. dept. of hematology, oncology, kermanshah university of medical sciences, kermanshah, iran 2. medical biology research center, kermanshah university of medical sciences, kermanshah, iran 3. students research committee, kermanshah university of medical sciences, kermanshah, iran     corresponding author: masoud sadeghi, msc; degree in biochemistry tel: (+91) 8338428221 email: [email protected] received: 07 feb. 2015 accepted: 22 feb. 2015 iran j cancer prev. 2015; 2:125-8.     abstract acute myelogenous leukemia (aml) is an aggressive hematologic malignancy that cause by abnormal proliferation and accumulation of hematopoietic progenitor cells. a 37-year-old woman referred to oncologic clinic with a self-detected mass and pain in her left breast. the stage of tumor was ιιιa. she was treated with the combination of anthracycline and cyclophosphamide for four courses, followed by four courses of paclitaxel with trastuzumab for one year. after 18 months of the first treatment for breast cancer, her bone marrow biopsy was compatible with aml-m2. here, we are reporting a young woman case with breast cancer that developed aml malignancy during short interval of therapy.

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Journal title:
iranian journal of cancer prevention

جلد ۸، شماره ۲، صفحات ۱۲۵-۱۲۸

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